The Gulfstream G450 is a direct descendent of the Gulfstream G400/GIV-SP series. Two Rolls Royce Tay MK 611-8C engines power the Gulfstream G450 each offering 13,850 (lbst) pounds of thrust and using a combined 401 gallons per hour (GPH). The range of the Gulfstream G450 is 4,328 nm operating under NBAA IFR 8 passengers with available fuel.

The cabin volume for the Gulfstream G450 is 1,525 cubic feet. Typical configuration features 14 passenger and 2 crew seats.